| Characteristics | Details |
|---|---|
| Active Ingredients | Metformin Hydrochloride, Sitagliptin Phosphate |
| Available Dosages | 50 mg/500 mg, 50 mg/1000 mg |
| Form | Tablets |
| Manufacturer | Merck & Co. |
| Therapeutic Class | Antidiabetic Agent |
| Prescription Status | Prescription Only |
| More on Janumet | |
Janumet combines metformin and sitagliptin. It targets type 2 diabetes mellitus. This combination helps control blood sugar levels. Metformin decreases glucose production. Sitagliptin increases insulin secretion.
Janumet is used with diet and exercise. It enhances glycemic control in adults. This drug addresses the inefficacy of monotherapy. It acts on several pathways. Patients often turn to Janumet when other options fail.
Dosage Information
Janumet 50 mg/500 mg and Janumet 50 mg/1000 mg are common dosages. The choice depends on patient needs. Administer tablets orally, twice daily. Take with meals to reduce gastrointestinal discomfort. Adjustments occur based on renal function. Start with a low dose to minimize side effects. Increase gradually, maintaining efficacy.
Monitor renal function periodically. This drug is not recommended in patients with severe renal impairment. A healthcare professional will determine the appropriate dose. Patients must adhere strictly to prescribed doses.
Janumet Contraindications
Janumet is not for everyone. It is contraindicated in severe renal impairment. Avoid in cases of metabolic acidosis, including diabetic ketoacidosis. Known hypersensitivity to metformin or sitagliptin requires avoidance.
Patients with liver disease should avoid Janumet. Alcohol abuse increases lactic acidosis risk. Disclose medical history to your healthcare provider. Janumet is unsuitable for individuals with type 1 diabetes.
Janumet Storage
Store Janumet in a cool, dry place. Keep away from direct sunlight. Temperatures should not exceed 25°C (77°F). Protect tablets from moisture.
Keep out of reach of children. Do not store in the bathroom. Expired medication should be discarded responsibly.
Adverse Effects
Possible adverse effects include gastrointestinal disturbances. Nausea and diarrhea are common. Rarely, lactic acidosis may occur.
Monitor for signs of pancreatitis. Allergic reactions might manifest as rash or hives. If any serious side effects appear, seek medical attention promptly.
Janumet Over The Counter
Janumet is not available over the counter. It requires a prescription. Only healthcare professionals can prescribe this medication.
Patients should not self-medicate. Consulting a healthcare provider is necessary. Appropriate assessment ensures safe use of Janumet.
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