| Characteristic | Details |
|---|---|
| Active Ingredient | Sitagliptin Phosphate |
| Dosage Form | Tablets |
| Available Strengths | 25mg, 50mg, 100mg |
| Indication | Type 2 Diabetes Mellitus |
| Manufacturer | Merck & Co., Inc. |
| Learn More | |
Chemical Structure of Januvia
The molecular formula of Januvia (Sitagliptin Phosphate) is C16H15F6N5O. This compound belongs to the DPP-4 inhibitors class. Its structure includes a triazolopyrazine moiety, characteristic of the gliptin family. Sitagliptin functions by selectively inhibiting the dipeptidyl peptidase-4 enzyme. This mechanism increases levels of incretin hormones, which regulate glucose homeostasis. The unique structural design ensures its effectiveness in managing glycemic control in patients with Type 2 Diabetes.
Guidelines for Using Januvia
Januvia 100mg is intended for oral use. Patients should ingest one tablet daily, with or without food. The dosage does not require adjustment based on food intake. Swallowing the tablet whole is crucial, avoiding any crushing or splitting. It’s essential to follow the prescribed dosage, maintaining consistency in administration time. Non-adherence might result in suboptimal therapeutic outcomes. Monitoring blood glucose levels periodically ensures efficacy and safety.
Precautions When Using Januvia
Patients with a history of pancreatitis should exercise caution. Alert healthcare providers about any persistent stomach pain. Renal function assessment is necessary before starting therapy, as Sitagliptin may require dosage adjustments in renal impairment. Pregnant or breastfeeding women should consult their doctor to weigh the benefits and potential risks.
Interactions with Other Medicines
Concomitant use with other antidiabetic medications may require dosage adjustment to minimize hypoglycemia risk. Patients taking strong CYP3A4 inhibitors need monitoring, as these may influence Sitagliptin plasma levels. Inform your healthcare provider about all ongoing treatments, including over-the-counter drugs and herbal supplements.
Possible Side Effects of Januvia
Most patients tolerate Januvia well. Common side effects include headaches and upper respiratory tract infections. Rare but serious reactions such as pancreatitis or hypersensitivity require immediate medical attention. Monitor for signs of allergic reactions, like rash or swelling, and report them promptly.
Where to Purchase Januvia Online
Online pharmacies provide a convenient option for purchasing Januvia. Ensure the platform is reputable, with certification for dispensing pharmaceuticals. Confirm the site requires a prescription, aligning with legal standards. Reviewing customer feedback and service reliability before ordering can guide a safe purchase experience.
Primary source:
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